Automated Blood Sampling System

PC and animal cage not included

Save your time, Save your blood.

Eicom automated blood sampling system, model DR-II is an automated blood aspirating robot for pharmacokinetics, drug metabolism, endocrinology and toxicology. The DR-II allows automatic and intermittent blood sampling via implanted catheter in a laboratory animal. This system was developed in order to eliminate the intensive labor of researchers and reduce the stress on animals caused by human interaction. Blood samples are aspirated from unrestrained animals by a syringe pump and collected in a refrigerated fraction collector. This sampling is carried out without dilution, cross contamination, hemolysis and blood coagulation. If blood can not be withdrawn because of catheter trouble, optical sensors find the trouble and remove it. The flow is controled by a 5-way joint, 4 pinch valves and a syringe pump. The DR-II withdraws blood samples with minimam loss and minimizes your labor.

Procedure

Sample blood is sandwiched by air gaps and the air gaps clean the inner surface of the tubing and thus prevent diffusion. Secondly, the DR-II is equipped with a special 5-way joint and 4 pinch valves which do not interfere the smooth inner surface of tubing, therefore not blood coagulation occurs in the tubing. Thirdly, the case of a low diffusion factor also helps eliminate any cross contamination.

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	Optical sensor system precisely controls sampling methods.
	The DR-II automatically calibrates the catheter volume.
	At most 16 units of the DR-II can be controlled simultaneously or independently by one PC (One DR-II carries out sampling from one catheter).
	GLP compliance; The sampling results of each fraction identified by sensors, clock time and others are registered.

Specifications
	Sample vial	Standard 1.5 mL centrifuge tubes
	Available blood vessel	Jugular vein,carotid artery, femoral artery/vein etc.
	Sample storage	Airtight by silicon sheet
	Sample storage temperature	4to ambient temperature, controlled in 1steps
	Type of fraction collector	12 low x 2 line (X-Y arm)
	Number of samples	1 to 480 (need to replace vials for more than 24 samples
	Maximum number of events	480 steps (sampling,flushing catheter or drag administration)
	Available lines for drug administration	The catheter for blood sampling and/or the other catheter*
	Maximum duration of sampling session	999h 59m 59s
	Auto-retry routine	Skip to next sample after twice attempts failed to withdraw blood
	Time to take one sample (minimum duration)	4 to 6 minutes by typical method (variables by parameter settings)
	Duration of cascade sampling	a few seconds,using high blood pressure for sampling
	Minimum collected sample volume	30 L
	Maximum collected sample volume	1500 L
	Chance of sample dilution	Less than 4% in case of 40 L collection Less than 0.5% in case of 250L
	Blood volume withdrawn per sample	165 L (in case of rats) + sample volume
	Blood to waste	Ca. 28 Ld.
	Saline volume returned to animal	55 L/sampling (in case of rats) + sample volume (programmable)
	Sensors	2 optical sensor
	Sampling needle washer	By water
	GLP compliance	Sampling results for each fraction, clock time and others are registered.
	Computer system requirements	Laptop or desktop with free 10/100 base-TX port, Windows98/ME/2000/XP, 128 MB RAM, 400MHz CPU
	Maximum number of samplers per computer	16
	Sampler communications method	Ethernet, UDP/IP protocol
	Computer-HUB and HUB-sampler cable	100 Base-TX category 5 straight cable
	Power supply	100-240 V
	Sampler power consumption	Less than 100 W
	Dimensions (W, D, H) / Weight	Fraction collector ; 330 x 210 x 310 / 8 kg Diluter ; 52 x 120 x 230 / 1.5 kg 5-way joint unit ; 80 x 42 x 100 / 0.5 kg Plastic cage ; 250 x 250 x 300
	Options	Microsyringe pump (ESP-32) for drug administration *2ch swivel for use of two catheters.
The specifications are subject to change without notice.