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Slice Chambers for Blind Patching & Extracellular Recording

745XX
Blind Patching & Extracellular Recording
Blind Patching & Extracellular Recording

Compact and modular; easy to set up, easy to swap between submerged and interface modes. Consistently stable fluid flow and stable temperature.

The Chambers:

  • Manufactured from Plexiglas, or, for pharmacological or toxicological studies chemically inert p.t.f.e. (Teflon®) to avoid adhesion of drugs.
  • Ag/AgCl reference electrodes included with termination points, easily replaceable
  • The one, two or four channel chambers can be used either in the classical submerged [Oslo type] or in the air/fluid interface [Haas Type] with humidified atmosphere above the tissue slices
  • To convert from submerged to interface type, simply exchange the chamber top plate
  • Heated water bath has a low noise heating element and gas tube to prevent oxygen loss from perfusate solution
  • Holding chamber for incubation of slices until transfer to recording chamber
  • Stable Temperature control by dual thermistor feedback from water bath and slice chamber
  • Ergonomic design for access from either side with micromanipulators

The Temperature Controller

  • Predictive algorithms [proportional integral derivative] gives very close control of to +/- 0.1 Celsius
  • Configurable alarms for temperature envelopes
  • No electromagnetic noise emission from the DC power source.
  • Temperature feedback from 2 thermistor probes, one can be placed in the chamber to check temperature, the other is permanently embedded with the perfusate tubes in the body of the chamber.
  • Digital and analogue data outputs are available
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